苏震-徐文英  实验室

 


| 研究方向| 实验室成员| 论文专利| 数据库| 网络资源| English Version|
  


 

苏震,教授,中国农业大学生物学院  [个人简历]

研究方向:农业生物信息学和系统生物学,着重于组学大数据
                         整合与解析的新技术和算法研究

实验室网页 http://www.systemsbiology.cn/ 
         E-mail
zhensu AT cau.edu.cn 
       

1990年毕业于北京农业大学应用物理专业,获理学士学位。1990至1997在中国科学院生物物理所细胞生物物理室工作,1994年起任助理研究员,从事光生物物理和辐射生物物理等领域的研究,其间发表论文20余篇。1997至2003就读于美国亚利桑那大学农业与生命科学学院,获得环境科学专业博士学位,副修材料工程专业,主要从事计算机分子模拟和生物信息数据挖掘的研究;其间自2001年起,先后就职于美国 TORREY MESA生物技术研究所(2001-2002,Bioinformatics Programmer)、ActivX生物医学公司(2002-2003,Bioinformatics Specialist)和Syngenta生物技术公司(2003-2004,Bioinformatics Scientist),从事功能基因组学和蛋白组学研究并负责基因芯片实验室信息管理系统的管理、维护和数据挖掘。

从2004年5月到中国农业大学至今,建立了生物信息平台,主持了生物信息学专业的学科建设,包括硕博生招生要求和培养方案等一系列工作,开设了以生物信息学为中心的不同层次要求的《生物信息学》、《生物信息学算法》和《生物信息学Seminar》等课程。作为课程负责人,主讲了四门生物信息学研究生的专业学位课程。共指导研究生40名,已毕业34名(博士27名,硕士7名),培养博士后2名 ,其中多人次获得各项奖励。

2009年入选教育部“新世纪优秀人才支持计划”,2018年获教育部高等学校科学研究优秀成果奖自然科学二等奖,2019年入选中国农业大学“人才培育发展支持计划”领军教授B类。自入校以来共发表SCI论文 84 篇(其中通讯作者论文60篇),SCI总他引6189次,Google Scholar引用为8498次,入选爱思唯尔2021“中国高被引学者”。

 

课题组主要研究方向为:

(1)整合多组学大数据(基因组学、转录组学、表观基因组学、蛋白质组学和代谢组学、变异组学、调控基因组学等),构建重要动植物功能基因组综合信息平台。建立了中国农业大学生物信息平台,致力于组学数据整合和挖掘、功能注释和节律性分析算法的方法学研究,发展了一系列的创新理论和技术体系,为组学数据分析挖掘提供了切实可行的途径,公开发布了20余个数据库和网络服务。

(2)通过多组学大数据分析,集成分析作物QTL和GWAS关联位点、表观遗传和转录调控位点、染色质状态和基因表达变化等关键信息,深入挖掘和解析关键调控因子和网络模块。正在试图建立一个集多功能于一体的水稻、玉米、大豆、棉花等作物调控基因组平台,以期加快基因组编辑技术在育种技术中的广泛应用,促进分子设计育种的发展。

(3)系统生物学研究:挖掘与生长发育和逆境应答相关的关键调控因子,开展与植物生长发育及逆境应答等相关的功能基因研究。比如,系统研究水稻和拟南芥SPX基因影响生长发育和环境应答的分子机制;探索拟南芥和棉花JAZ家族基因在叶片衰老和水分胁迫适应性的分子机制;对植物时序(如昼夜节律变化,叶片衰老等)的动态基因表达调控和表观遗传变化的规律进行探索,以期发现时序转录调控的关键因子,并尝试跨物种表观基因组比较分析(包括拟南芥、水稻、棉花和玉米等)。

 

发表文章:(*通讯作者)

Zhongqiu Li, Yiheng Hu, Xuelian Ma, Lingling Da, Jiajie She, Yue Liu, Xin Yi, Yaxin Cao, Wenying Xu, Yuannian Jiao*, Zhen Su*. (2022). WheatCENet: A database for comparative co-expression networks analysis of allohexaploid wheat and its progenitors.  Genomics, Proteomics & Bioinformatics.  doi: 10.1016/j.gpb.2022.04.007.

Minghao Sheng, Lingling Da, Qian Song, Yue Liu, Xinyi Zhang, Fengxia Liu, Wenying Xu, Zhen Su*. (2022). Systems biology-based analysis indicates that PHO1;H10 positively modulates high light-induced anthocyanin biosynthesis in Arabidopsis leaves.  Genomics.  doi: 10.1016/j.ygeno.2022.110363.

Jiaotong Yang, Hengyu Yan, Yue Liu, LingLing Da, Wenying Xu*, Qiaoqiao Xiao*, Zhen Su*. (2022). GURFAP: a platform for gene function analysis in Glycyrrhiza uralensis.  Frontiers in Genetics.  doi: 10.3389/fgene.2022.823966.

Minghao Sheng, Xuelian Ma, Jiyao Wang, Tianxi Xue, Zhongqiu Li, Yaxin Cao, Xinyue Yu, Xinyi Zhang, Yonghong Wang, Wenying Xu, Zhen Su*. (2022). KNOX II Transcription Factor HOS59 Functions in Regulating Rice Grain Size. Plant Journal. doi:10.1111/tpj.15709.

Huawei Liu, Li Jiang, Zhifeng Wen, Yingjun Yang, Stacy D. Singer, Dennis Bennett, Wenying Xu, Zhen Su, Zhifang Yu, Jonathan Cohn, Hyunsook Chae, Qiudeng Que, Yue Liu, Chang Liu, Zongrang Liu. (2021). Rice RS2-9, which is bound by transcription factor OSH1, blocks enhancer-promoter interactions in plants. Plant Journal. 109: 541–554.

Xuelian Ma, Hengyu Yan, Jiaotong Yang, Yue Liu, Zhongqiu Li, Minghao Sheng, Yaxin Cao, Xinyue Yu, Xin Yi, Wenying Xu, Zhen Su*. (2021). PlantGSAD: a comprehensive gene set annotation database for plant species. Nucleic Acids Research. 50: D1456–D1467.

Qiaoqiao Xiao, Zhongqiu Li, Mengmeng Qu, Wenying Xu, Zhen Su*, Jiaotong Yang*. (2021). LjaFGD: Lonicera japonica functional genomics database. Journal of Integrative Plant Biology. doi: 10.1111/jipb.13112.

Xuelian Ma, Hansheng Zhao, Hengyu Yan, Minghao Sheng, Yaxin Cao, Kebin Yang, Hao Xu, Wenying Xu*, Zhimin Gao*, Zhen Su*. (2021). Refinement of bamboo genome annotations through integrative analyses of transcriptomic and epigenomic data. Computational and Structural Biotechnology Journal. PII: S2001-0370(21)00180-X. doi: 10.1016/j.csbj.2021.04.068.

Peng Yu, Xiaoming He, Marcel Baer, Stien Beirinckx, Tian Tian, Yudelsy A. T. Moya, Xuechen Zhang, Marion Deichmann, Felix P. Frey, Verena Bresgen, Chunjian Li, Bahar S. Razavi, Gabriel Schaaf, Nicolaus von Wirén, Zhen Su, Marcel Bucher, Kenichi Tsuda, Sofie Goormachtig, Xinping Chen and Frank Hochholdinger. (2021). Plant flavones enrich rhizosphere Oxalobacteraceae to improve maize performance under nitrogen deprivation.  Nature Plants. 7:481–499. 

Jiaotong Yang, Qiaoqiao Xiao, Jiao Xu, Lingling Da, Lanping Guo, Luqi Huang, Yue Liu, Wenying Xu, Zhen Su, Shiping Yang, Qi Pan, Weike Jiang and Tao Zhou. (2020). GelFAP: Gene functional analysis platform for Gastrodia elata. Frontiers in Plant Science. 11:563237.

Minghao Sheng, Jiajie She, Wenying Xu, Yan Hong, Zhen Su* and Xiaodong Zhang*. (2020). HpeNet: Co-expression Network Database for De Novo Transcriptome Assembly of Paeonia lactiflora Pall.  Frontiers in Genetics. 11:570138.

Nannan Zhao, Kang Zhang, Chunchao Wang, Hengyu Yan, Yue Liu, Wenying Xu* and Zhen Su*. (2020). Systematic analysis of differential H3K27me3 and H3K4me3 deposition in callus and seedling reveals the epigenetic regulatory mechanisms involved in callus formation in rice. Frontiers in Genetics. 11:766.

Nannan Zhao, Minghao Sheng, Jie Zhao, Xuelian Ma, Qiang Wei, Qian Song, Kang Zhang, Wenying Xu, Chuanqing Sun, Fengxia Liu* and Zhen Su*. (2020). Over-expression of HDA710 delays leaf senescence in rice (Oryza sativa L.). Frontiers in Bioengineering and Biotechnology. 8:471.

Jiongliang Wang, Xuelian Ma, Jiaotong Yang, Wenying Xu, Yanan Hui, Jiajie She, Tian Tian, Zhongqiu Li, Zhimin Gao, Zhen Su* and Hansheng Zhao*. (2020). Co-expression network analysis reveals the dynamic modules regulating the growth and development of cirrus in the rattans (Calamus simplicifolius and Daemonorops jenkinsiana). Frontiers in Genetics. 11:378.

Ge Zhao, Yun Song, Qianhua Wang, Dongxia Yao, Dongliang Li, Wenqiang Qin, Xiaoyang Ge, Zuoren Yang, Wenying Xu, Zhen Su, Xueyan Zhang, Fuguang Li, Jiahe Wu. (2020). Gossypium hirsutum salt tolerance is enhanced by overexpression of G. arboreum JAZ1. Frontiers in Bioengineering and Biotechnology. 8:157.

Lingling Da, Yue Liu, Jiaotong Yang, Tian Tian, Jiajie She, Xuelian Ma, Wenying Xu*, Zhen Su*. (2019). AppleMDO: A multi-dimensional omics database for apple co-expression networks and chromatin states. Frontiers in Plant Science. 10:1333.

Yuan Fang, Lifen Chen, Kande Lin, Yilong Feng, Pengyue Zhang, Xiucai Pan, Jennifer Sanders, Yufeng Wu, Xiu-e Wang, Zhen Su, Caiyan Chen, Hairong Wei, Wenli Zhang. (2019). Characterization of functional relationships of R-loops with gene transcription and epigenetic modifications in rice. Genome Research. doi: 10.1101/gr.246009.118.

Hengyu Yan, Yue Liu, Kang Zhang, James Song, Wenying Xu*, Zhen Su*. (2019). Chromatin state-based analysis of epigenetic H3K4me3 marks of Arabidopsis in response to dark stress. Frontiers in Genetics. 10:306.

Hengyu Yan, Minghao Sheng, Chunchao Wang, Yue Liu, Jiaotong Yang, Fengxia Liu, Wenying Xu*, Zhen Su*. (2019). AtSPX1-mediated transcriptional regulation during leaf senescence in Arabidopsis thaliana. Plant Science. doi:10.1016/j.plantsci.2019.03.005.

Jiajie She, Hengyu Yan, Jiaotong Yang, Wenying Xu*, Zhen Su*. (2019). croFGD: Catharanthus roseus Functional Genomics Database. Frontiers in Genetics. 10:238.

Jiaotong Yang, Yue Liu, Hengyu Yan, Tian Tian, Qi You, Liwei Zhang, Wenying Xu*, Zhen Su*. (2018). PlantEAR: functional analysis platform for plant EAR motif-containing proteins. Frontiers in Genetics. 9:590.

Xuelian Ma, Hansheng Zhao, Wenying Xu, Qi You, Hengyu Yan, Zhimin Gao*, Zhen Su*. (2018). Co-expression Gene Network Analysis and Functional Module Identification in Bamboo Growth and Development. Frontiers in Genetics. 9:574.

Tian Tian, Qi You, Hengyu Yan, Wenying Xu*, Zhen Su*. (2018). MCENet: A database for maize conditional co-expression network and network characterization collaborated with multi-dimensional omics levels. Journal of Genetics and Genomics. 45: 351-360.

Zhaobin Dong, Juan Yu, Hui Li, Wei Huang, Ling Xu, Yue Zhao, Tao Zhang, Wenying Xu, Jiming Jiang, Zhen Su*, Weiwei Jin*. (2018). Transcriptional and epigenetic adaptation of maize chromosomes in Oat-Maize addition lines. Nucleic Acids Research. 46: 5012–5028.

Yue Liu, Tian Tian, Kang Zhang, Qi You, Hengyu Yan, Nannan Zhao, Xin Yi, Wenying Xu*, Zhen Su*. (2017). PCSD: A plant chromatin state database. Nucleic Acids Research.  doi:10.1093/nar/gkx919.

Hansheng Zhao, Shancen Zhao, International Network for Bamboo and Rattan, Benhua Fei, Huan Liu, Huanming Yang, Honghai Dai, DanWang, Wei Jin, Feng Tang, Qiang Gao, Hang Xun, Yuwei Wang, Lianghua Qi, Xianghua Yue, Shuyan Lin, Lianfeng Gu, Lubin Li, Tiansheng Zhu, Qiang Wei, Zhen Su, Tarmeze Bin Wanoup Ariffin Wan, Daniel A. Ofori, George Mbeva Muthike, Yigardu Mulatu Mengesha, Roberto Magno de Castro e Silva, Antonio Ludovico Beraldo, Zhimin Gao, Xin Liu, Zehui Jiang. (2017). Announcing the Genome Atlas of Bamboo and Rattan (GABR) project: promoting research in evolution and in economically and ecologically beneficial plants. GigaScience. 6: 1–7.

Qi You, Xin Yi, Kang Zhang, Chunchao Wang, Xuelian Ma, Xueyan Zhang, Wenying Xu, Fuguang Li*, Zhen Su*. (2017). Genome-wide comparative analysis of H3K4me3 profiles between diploid and allotetraploid cotton to refine genome annotation. Scientific Reports. doi:10.1038/s41598-017-09680-6.

Yue Liu, Wenli Zhang, Kang Zhang, Qi You, Hengyu Yan, Yuannian Jiao, Jiming Jiang, Wenying Xu, Zhen Su*. (2017). Genome-wide mapping of DNase I hypersensitive sites reveals chromatin accessibility changes in Arabidopsis euchromatin and heterochromatin regions under extended darkness. Scientific Reports. doi:10.1038/s41598-017-04524-9.

Tian Tian, Yue Liu, Hengyu Yan, Qi You, Xin Yi, Zhou Du, Wenying Xu*, Zhen Su*. (2017). agriGO v2.0: a GO analysis toolkit for the agricultural community, 2017 update. Nucleic Acids Research. doi:10.1093/nar/gkx382.

Kang Zhang, Wenying Xu, Chunchao Wang, Xin Yi, Zhen Su*. (2017). Differential deposition of H2A.Z in rice seedling tissue during the day-night cycle. Plant Signaling & Behavior.  doi:10.1080/15592324.2017.1286438.

Qi You, Hengyu Yan, Yue Liu, Xin Yi, Kang Zhang, Wenying Xu* and Zhen Su*. (2016). A systemic identification approach for primary transcription start site of Arabidopsis miRNAs from multidimensional omics data. Functional & Integrative Genomics. doi:10.1007/s10142-016-0541-9.

Qi You, Wenying Xu, Kang Zhang, Liwei Zhang, Xin Yi, Dongxia Yao, Chunchao Wang, Xueyan Zhang, Xinhua Zhao, Nicholas Provart, Fuguang Li*, Zhen Su*. (2016). ccNET: Database of co-expression networks with functional modules for diploid and polyploid Gossypium. Nucleic Acids Research. 45: D1090–D1099.

Qi You, Liwei Zhang, Xin Yi, Kang Zhang, Dongxia Yao, Xueyan Zhang, Qianhua Wang, Xinhua Zhao, Yi Ling, Wenying Xu*, Fuguang Li*, Zhen Su*. (2016). Co-expression network analyses identify functional modules associated with development and stress response in Gossypium arboreum. Scientific Reports. 6, 38436

Zhang, K., Xu, W., Wang, C., Yi, X., Zhang, W*. and Su, Z*. (2016). Differential deposition of H2A.Z in combination with histone modifications within related genes in rice callus and seedling. Plant J.  doi:10.1111/tpj.13381.

Yuan Fang, Lei Wang, Ximeng Wang, Qi You, Xiucai Pan, Jin Xiao, Xiu-e Wang, Yufeng Wu, Zhen Su*, Wenli Zhang* (2016). Histone modifications facilitate the coexpression of bidirectional promoters in rice. BMC Genomics. 17:768

Tian Tian, Qi You, Liwei Zhang, Xin Yi, Hengyu Yan, Wenying Xu*, Zhen Su* (2016). SorghumFDB: Sorghum Functional Genomics Database with multidimensional network analysis. Database doi:10.1093/database/baw099.

Xin Ma, Yongcai Fu, Xinhui Zhao, Liyun Jiang, Zuofeng Zhu, Ping Gu, Wenying Xu, Zhen Su, Chuanqing Sun & Lubin Tan (2016). Genomic structure analysis of a set of Oryza nivara introgression lines and identification of yield associated QTLs using wholegenome resequencing. Scientific Reports   doi: 10.1038/srep27425.

Kang Zhang, Qian Song, Qiang Wei, Chunchao Wang, Liwei Zhang, Wenying Xu*, Zhen Su* (2016). Down-regulation of OsSPX1 caused semi-male sterility, resulting in reduction of grain yield in rice. Plant Biotechnology Journal   doi:10.1111/pbi.12527.

Juan Yu, Yixiang Zhang, Chao Di, Qunlian Zhang, Kang Zhang, Chunchao Wang, Qi You, Hong Yan, Susie Dai, Joshua Yuan*, Wenying Xu*, and Zhen Su* (2015). JAZ7 negatively regulates dark-induced leaf senescence in Arabidopsis. Journal of Experimental Botany doi:10.1093/jxb/erv487.

Zhenyan Miao; Wei Xu; Daofeng Li; Xiaona Hu; Jiaxing Liu; Rongxue Zhang; Zongyong Tong; Jiangli Dong; Zhen Su; Liwei Zhang; Min Sun; Wenjie Li; Zhenglin Du; Songnian Hu; Tao Wang (2015). De novo transcriptome analysis of Medicago falcata reveals novel insights about the mechanisms underlying abiotic stress-responsive pathway. BMC Genomics 16:818. doi:10.1186/s12864-015-2019-x.

Xu W, Di C, Zhou S, Liu J, Li L, Liu F, Yang X, Ling Y* and Su Z* (2015). Rice Transcriptome Analysis to Identify Possible Herbicide Quinclorac Detoxification Genes. Front. Genet. 6:306. doi: 10.3389/fgene.2015.00306.

Jinyan Guo, Gongyao Shi, Liwei Zhang, Wenying Xu, Yumei Wang, Zhen Su*, Jinping Hua*. (2015) Transcriptome analysis reveals that distinct metabolic pathways operate in salt-tolerant and salt-sensitive upland cotton varieties subjected to salinity stress. Plant Science. doi:10.1016/j.plantsci.2015.05.013.

Liwei Zhang, Jinyan Guo, Qi You, Xin Yi, Yi Ling, WenyingXu, Jinping Hua*, Zhen Su*. (2015) GraP: Platform for Functional Genomics Analysis of Gossypium raimondii. Database. doi:10.1093/database/bav047.

Qi You, Liwei Zhang, Xin Yi, Zhenghai Zhang, Wengying Xu*, and Zhen Su*. (2015) SIFGD: Setaria italica Functional Genomics Database. Molecular Plant. doi:10.1016/j.molp.2015.02.001.

Xin Yi, Zhenhai Zhang, Yi Ling, Wenying Xu*, Zhen Su*. (2015) PNRD: A plant non-coding RNA database. Nucleic Acids Research. 43: D982-D989.

Yonglu Meng, Nan Ma, Qian Zhang, Qi You, Na Li, Muhammad Ali Khan, Xiaojing Liu, Lin Wu, Zhen Su and Junping Gao. (2014) Precise Spatio-Temporal modulation of ACC Synthase by MPK6 Cascade Mediates the Response of Rose Flower to Rehydration. The Plant Journal. doi:10.1111/tpj.12594.

Juan Yu, Zhenhai Zhang, Jiangang Wei, Yi Ling, Wenying Xu*, Zhen Su*. (2014) SFGD: a comprehensive platform for mining functional information from soybean transcriptome data and its use in identifying acyl-lipid metabolism pathways. BMC Genomics. 15:271.

Chunchao Wang, Qiang Wei, Kang Zhang, Ling Wang, Fengxia Liu, Linna Zhao, Yuanjun Tan, Chao Di, Hong Yan, Jingjuan Yu, Chuanqing Sun, Wenqiong J Chen, Wenying Xu*, Zhen Su*. (2013) Down-regulation of OsSPX1 causes high sensitivity to cold and oxidative stresses in rice seedlings. PLoS ONE. doi:10.1371/journal.pone.0081849.

Du Z, Fei T, Verhaak RGW, Su Z, Zhang Y, Brown M, Chen C, Liu XS. (2013) An integrated approach to identify clinically relevant long non-coding RNAs (IncRNAs) in cancer. Nat Struct Mol Biol. doi:10.1038/nsmb.2591.

Xin Yi, Zhou Du*, Zhen Su*. (2013) PlantGSEA: a Gene Set Enrichment Analysis toolkit for plant community.  Nucleic Acids Research. doi:10.1093/nar/gkt281.

Zhou Du, Hui Li, Qiang Wei, Xin Zhao, Chunchao Wang, Qilin Zhu, Xin Yi, Wenying Xu, X. Shirley Liu*, Weiwei Jin*, Zhen Su*. (2013) Genome-wide analysis of histone modifications: H3K4me2, H3K4me3, H3K9ac and H3K27ac, in Oryza sativa L. japonica.  Molecular Plant. doi:10.1093/mp/sst018.

Xueyan Zhang, Dongxia Yao, Qianhua Wang, Wenying Xu, Qiang Wei, Chunchao Wang, Chuanliang Liu, Chaojun Zhang, Hong Yan, Yi Ling, Zhen Su*, Fuguang Li*. (2013) mRNA-seq analysis of the Gossypium arboreum transcriptome reveals tissue selective signaling in response to water stress during seedling stage. PLoS ONE. doi:10.1371/journal.pone.0054762.

Fengxia Liu, Wenying Xu, Qian Song, Lubin Tan, Jiayong Liu, Zuofeng Zhu, Yongcai Fu, Zhen Su*, and Chuanqing Sun*. (2013) Microarray Assisted Fine-mapping of Quantitative Trait Loci for Cold Tolerance in Rice. Molecular Plant. doi:10.1093/mp/sss161.

Gaihua Zhang, Yijing Zhang and Zhen Su*. (2012) CYPSI: a structure-based interface for cytochrome P450s and ligands in Arabidopsis thaliana. BMC Bioinformatics. 13:332.

Gaihua Zhang and Zhen Su*. (2012) Inferences from structural comparison: flexibility, secondary structure wobble and sequence alignment optimization. BMC Bioinformatics. 13(Suppl 15):S12.

Dongxia Yao, Qiang Wei, Wenying Xu, Ryan D Syrenne, Joshua S. Yuan, and Zhen Su*. (2012) Comparative genomic analysis of NAC transcriptional factors to dissect the regulatory mechanisms for cell wall biosynthesis. BMC Bioinformatics. 13(Suppl 15):S10.

Zhenyan Miao, Daofeng Li, Zhenhai Zhang, Jiangli Dong, Zhen Su* and Tao Wang*. (2012) Medicago truncatula transporter database: a comprehensive database resource for M. truncatula transporters. BMC Genomics. 13:60.

Daofeng Li, Yunqin Zhang, Xiaona Hu, Xiaoye Shen, Lei Ma, Zhen Su, Tao Wang and Jiangli Dong. (2011) Transcriptional profiling of Medicago truncatula under salt stress identified a novel CBF transcription factor MtCBF4 that plays an important role in abiotic stress responses. BMC Plant Biology. 11:109.

Dongxia Yao, Xueyan Zhang, Xinhua Zhao, Chuanliang Liu, Chunchao Wang, Zhenghai Zhang, Chaojun Zhang, Qiang Wei, Qianhua Wang, Hong Yan, Fuguang Li*, Zhen Su*. (2011) Transcriptome analysis reveals salt-stress-regulated biological processes and key pathways in roots of cotton (Gossypium hirsutum L.). Genomics. 98: 47–55

Wenying Xu, Rendong Yang, Meina Li, Zhuo Xing, Wenqiang Yang, Guang Chen, Han Guo, Xiaojie Gong, Zhou Du, Zhenhai Zhang, Xingming Hu, Dong Wang, Qian Qian, Tai Wang, Zhen Su*, Yongbiao Xue*. (2011)   Transcriptome Phase Distribution Analysis Reveals Diurnal Regulated Biological Processes and Key Pathways in Rice Flag Leaves and Seedling Leaves. PLoS ONE doi:10.1371/journal.pone.0017613

Rendong Yang, Chen Zhang, Zhen Su*. (2011)   LSPR: an integrated periodicity detection algorithm for unevenly sampled temporal microarray data. Bioinformatics. 27: 1023-1025

Yi Ling, Zhou Du, Zhenhai Zhang and Zhen Su*. (2010)  ProFITS of maize: a database of protein families involved in the transduction of signalling in the maize genome. BMC Genomics. 11:580.

Chao Di, Wenying Xu, Zhen Su* and Joshua S Yuan*. (2010) Comparative genome analysis of PHB gene family reveals deep evolutionary origins and diverse gene function. BMC Bioinformatics. 11 (Suppl 6):S22.

Li Q Wei, Wen Y Xu, Zhu Y Deng, Zhen Su, Yongbiao Xue and Tai Wang. (2010) Genome-scale Analysis and Comparison of Gene Expression Profiles in Developing and Germinated Pollen in Oryza sativa. BMC Genomics. 11:338.

Rendong Yang and Zhen Su*. (2010) Analyzing circadian expression data by harmonic regression based on autoregressive spectral estimation. BIOINFORMATICS. 26: i168-i174.

Zhou Du , Xin Zhou , Yi Ling , Zhenhai Zhang , and Zhen Su*. (2010) agriGO: a GO analysis toolkit for the agricultural community. Nucleic Acids Research  38: W64-W70.

Jie Zhang, Haibin Lu, Xinyan Li, Yan Li, Haitao Cui, Chi-Kuang Wen, Xiaoyan Tang, Zhen Su, and Jian-Min Zhou (2010) Effector-Triggered and Pathogen-Associated Molecular Pattern–Triggered Immunity Differentially Contribute to Basal Resistance to Pseudomonas syringae. Molecular Plant-Microbe Interactions. 23: 940–948.

Liu F, Xu W, Wei Q, Zhang Z, Xing Z, Tan L, Di C, Yao D, Wang C, Tan Y, Yan H, Ling Y, Sun C, Xue Y*, Su Z.* (2010) Gene Expression Profiles Deciphering Rice Phenotypic Variation between Nipponbare (Japonica) and 93-11 (Indica) during Oxidative Stress. PLoS ONE 5(1): e8632.

Zhenhai Zhang, Jingyin Yu, Daofeng Li, Zuyong Zhang, Fengxia Liu, Xin Zhou, Tao Wang, Yi Ling, and Zhen Su*. (2010)  PMRD: plant microRNA database. Nucleic Acids Research. 38: D806-D813

Daofeng Li, Zhen Su, Jiangli Dong and Tao Wang. (2009)  An expression database for roots of the model legume Medicago truncatula under salt stress. BMC Genomics. 10:517

Xin Zhou, Zhen Su, R Douglas Sammons, Yanhui Peng, Patrick J Tranel, C Neal Stewart Jr, and Joshua S Yuan. (2009) Novel software package for cross-platform transcriptome analysis (CPTRA). BMC Bioinformatics. 10 (Suppl 11):S16

Fu-Qing Wu, Qi Xin, Zheng Cao, Zhi-Qiang Liu, Shu-Yuan Du, Chao Mei, Chen-Xi Zhao, Xiao-Fang Wang, Yi Shang, Tao Jiang, Xiao-Feng Zhang, Lu Yan, Rui Zhao, Zi-Ning Cui, Rui Liu, Hai-Li Sun, Xin-Ling Yang, Zhen Su, and Da-Peng Zhang. (2009) The Mg-Chelatase H Subunit Binds Abscisic Acid and Functions in Abscisic Acid Signaling: New Evidence in Arabidopsis. Plant Physiol. 150(4):1940-54

Zhou Du, Xin Zhou, Li Li, Zhen Su*. (2009) plantsUPS: a database of plants' Ubiquitin Proteasome System. BMC Genomics. 10:227

郭华军, 焦远年, 邸超, 姚冬霞, 张盖华, 郑雪, 刘岚, 张群莲, 郭蔼光*, 苏震* (2009). 拟南芥转录因子GRAS 家族基因群响应渗透和干旱胁迫的初步探索. 植物学报 44, 290-299.

Linna Zhao, Fengxia Liu, Wenying Xu, Chao Di, Shaoxia Zhou, Yongbiao Xue, Jingjuan Yu*, Zhen Su*. (2009) Increased expression of OsSPX1 enhances cold/subfreezing tolerance in tobacco and Arabidopsis thaliana. Plant Biotechnology Journal. 7: 550-561.

Hao Lin, Renxiao Wang, Qian Qian, Meixian Yan, Xiangbing Meng, Zhiming Fu, Cunyu Yan, Biao Jiang, Zhen Su, Jiayang Li, Yonghong Wang. (2009) DWARF27, an Iron-Containing Protein Required for the Biosynthesis of Strigolactones, Regulates Rice Tiller Bud Outgrowth through the MAX/RMS/D Pathway. Plant Cell. 21:1512-1525

Zhi-yu Peng, Xin Zhou, Linchuan Li, Xiangchun Yu, Hongjiang Li, Zhiqiang Jiang, Guangyu Cao, Mingyi Bai, Xingchun Wang, Caifu Jiang, Haibin Lu, Xianhui Hou, Lijia Qu, Zhiyong Wang, Jianru Zuo, Xiangdong Fu, Zhen Su, Songgang Li, and Hongwei Guo. (2009) Arabidopsis Hormone Database: a comprehensive genetic and phenotypic information database for plant hormone research in Arabidopsis. Nucleic Acids Research. 37: D975-D982

Xin Zhou, Zhen Su*. (2008) tCal: transcriptional probability calculator using thermodynamic model. Bioinformatics. 24: 2639 - 2640

He Fei, Kang Juqing, Zhou Xin, Su Zhen, Qu Li-Jia, Gu Hongya. (2008) Variation at the transcriptional level among Chinese natural populations of Arabidopsis thaliana in response to cold stress. Chinese Science Bulletin. Vol.53  No. 19  pp.2989-2999

Yi Wang, Wen-Zheng Zhang, Lian-Fen Song, Jun-Jie Zou, Zhen Su, and Wei-Hua Wu. (2008) Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis. Plant Physiol.  148:1201-1211

Liu, F., Xu, W.*, Tan, L., Xue, Y., Sun, C., Su, Z.* (2008) Case study for identification of indel-caused alternative expression isoforms in rice subspecies japonica and indica by integrative genome analysis. Genomics 91: 186–194

Xin Zhou, Zhen Su*. (2007) EasyGO: Gene Ontology-based annotation and functional enrichment analysis tool for agronomical species, BMC Genomics 8:246

Hou ZC, Xu GY, Su Z, Yang N. 2007Purifying selection and positive selection on the myxovirus resistance gene in mammals and chickens. Gene. 396(1):188-95.

Xin Zhou, Fei He, Fengxia Liu, Xue Zheng, Chao Di, Shaoxia Zhou, Hongya Gu, Wenying Xu, and Zhen Su*. (2006) Integration of Cold Signal Transduction Pathway Related to ABA 8’-hydroxylase in Arabidopsis. Biotechnology and Sustainable Agriculture 2006 and Beyond, 471-474, Z. Xu et al. (eds.), 2007 Springer

Jia J, Fu J, Zheng J, Zhou X, Huai J, Wang J, Wang M, Zhang Y, Chen X, Zhang J, Zhao J, Su Z, Lv Y, Wang G. (2006) Annotation and expression profile analysis of 2073 full-length cDNAs from stress-induced maize (Zea mays L.) seedlings. Plant J. 48(5):710-27.

Zhang X, Zhou S, Fu Y, Su Z, Wang X, Sun C. (2006) Identification of a drought tolerant introgression line derived from Dongxiang common wild rice (O. rufipogon Griff.). Plant Mol Biol. 62(1-2):247-59.

丁必为,田英杰,邓乃扬,苏震,蔡春. (2006) 基于支持向量机的拟南芥基因表达数据分析. 运筹学学报10(2):51-58

刘云岩,苏震,董江丽,申小叶,李道丰,王涛 (2006) 截形苜蓿生物数据分析平台的构建与应用 草地学报 14(3): 231-235

刘胜毅, 毛晗, 苏震, 董彩华, 徐文英, 冀瑞琴, 郭学兰. (2005)  油菜对菌核病和黑胫病的抗病机制分析. 西北农林科技大学学报(自然科学版)   2005z1

Su Z, Cushman JH, Curry JE (2003) Computer simulation of anisotropic diffusion in monolayer films in mica slit pores. Journal of Chemical Physics, 118(3):1417-1422

 苏震, 徐文英, 张仲纶, 马玉琴, 傅翠真, 郑雁珍, 刘成祥. (1997) 大豆种子脂肪氧化酶同工酶缺失体的超弱发光研究  《大豆科学》  1997(3)

赵文恩, 韩雅珊, Saishi Hirota, 苏震, 张仲纶, 郑雁珍. (1997) 类胡萝卜素对H2O2-NaOCl体系生成的1O2的猝灭作用  《生物物理学报》  1997(1) : 137-142

傅翠真, 徐文英, 苏震. (1997) 中国大豆脂肪氧化酶缺失种质多样性鉴定研究《中国农业科学》1997(1)

章汴生, 牛玉中, 阎日成, 马玉琴, 张仲伦, 苏震. (1997)  人血清超弱发光水平与肿瘤关系的研究  《肿瘤研究与临床》  1997 (1)

徐文英, 傅翠真, 苏震. (1996) 大豆脂肪氧化酶的研究动态  《植物生理学通讯》    1996 (4) : 308-313

Wang Yingyan, Wang Jinguang, Ma Yuqin, Su Zhen, Zhang Zhonglun, Zheng Yanzhen, Liu Chengxiang. (1996) Biophoton emission, free radical and toxicity of benzene to aquatic biosystems   Journal of Environmental Sciences. Vol.8  No.2: 218-227

徐文英, 付翠真, 丁安林, 苏震, 马玉琴, 张仲纶. (1995)  大豆脂肪氧化酶同工酶缺失体的苗期叶片超弱发光研究   《大豆科学》 1995 (3)

Ma Yuqin, Zhang Zhonglun, Su Zhen, Ma Bin, Zheng Yanzhen, Liu Chengxiang, Wang Yingyan, Wa Jiguang. (1995) SO2-induced change of spectrum in Low-Level Chemiluminescence from Populus tomentosa leaf.  Bull. Environ. Contam. Toxicol.   Vol. 55: 136-141

王英彦, 马玉琴, 苏震, 张仲纶, 郑雁珍, 刘成祥. (1995)  苯、过渡金属离子和鱼肝微粒体相互作用过程中的生物光子发射     《科学通报》  1995 (20)

王英彦, 王继光;马玉琴, 苏震, 赵克俭, 张仲纶, 郑雁珍, 刘成祥. (1995)  60Coγ射线辐照诱发的苯水体系发光特性的实验研究      《化学通报》 1995 (1) 31-33

苏 震, 马玉琴, 张仲纶, 赵克俭, 郑雁珍, 马斌, 刘成祥. (1994) 血清的超弱发光对骨肿瘤术前术后监测的临床意义   《中国肿瘤临床》 1994 (12) 903-905

苏 震, 马玉琴, 张仲纶, 赵克俭, 宗小林, 郑雁珍, 刘成祥. (1994)   毛白杨叶片SO2急性损伤诱发的呼吸障碍与其低水平化学发光的相关性研究   《科学通报》 1994(20) 1893-1895

张仲纶, 郑雁珍, 苏震, 马玉琴, 赵克俭, 刘成祥, 马斌;卢绍婉, 孙象贤, 王淑贤, 叶元贞, 尹殿军;糜福顺, 苏学清.  (1994)   单片微机化微弱发光测量仪及其在肿瘤研究中的初步应用 《生物医学工程学杂志》 1994 (1) 24-30

马玉琴, 张仲纶, 苏震, 郑雁珍, 马斌, 刘成祥, 赵克俭;王英彦, 王继光.  (1994)     SO2诱导的毛白杨叶片LCL发射光谱变化 《科学通报》 1994 (6)

马玉琴, 赵克俭, 张仲纶, 苏震, 马斌, 郑雁珍, 杨光洁, 米志勇  (1994)   羟自由基(*OH)、超氧阴离子(O2)与线粒体低水平化学发光相关性的研究  《感光化学与光化学》  1994 (4) 312-317

常崴克, 唐锦华, 罗醒萱;张仲纶, 苏震, 刘成祥, 郑雁珍  (1994)  快中子治癌束剂量特性研究    《辐射防护》 1994 (4) 256-261

张仲纶, 苏震, 郑雁珍, 刘晓梅.  (1993)  LiF剂量计高剂量测量方法研究 《辐射研究与辐射工艺学报》 1993(3) 135-138

张仲纶, 郑雁珍, 苏震, 赵克俭, 刘成祥. (1993)  中国实验卫星中空间辐射剂量的热释光分析方法   《空间科学学报》 1993 (2)

Wang Yingyan, Ma Yuqin, Su Zhen, Wang Jinguang, Zhao Keijian, Zhang Zhonglun, Ma Bin, Zheng Yanzhen, Liu Chengxiang. (1993) Changes of Low Level Chemiluminescence Spectra from Plant Leaf Smoked by Air Pollutants   Fresenius Envir Bull   2: 588-595

王红霞, 袁润英, 相东, 王林, 吴捷, 徐万鹏;马玉琴, 赵克俭, 张仲纶, 苏震, 郑雁珍, 马斌.  (1993)   骨肿瘤病人血清和尿液超微弱发光强度的研究   《中华肿瘤杂志》  1993 (2) 108-111

马斌, 马玉琴, 苏震, 赵克俭, 张仲纶, 郑雁珍, 刘成祥, 王英彦.  (1992)  雨水对毛白杨树叶片低水平化学发光的影响 《科学通报》 1992 (24)

Ma Yuqin, Zhao Kejian, Zhang Zhonglun, Su Zhen, Ma Bin, Zheng Yanzhen, Liu Chengxiang. (1992) Influence of Rain and Sulphur Dioxide on Low-Level Chemiluminescence from leaf of Populus tomentosa     Bull. Environ. Contam. Toxicol.   Vol. 49  906-913

马玉琴, 赵克俭, 王英彦, 张仲纶, 郑雁珍, 苏震, 马斌, 刘成祥, 韩卫.  (1992)      用斑马鱼的自发化学发光研究水域酚污染  《环境保护》 1992 (11) 33-34

Ma Yuqin, Song Xueling, Zhao Kejing, Zhang Zhoglun, Ma Bin, Zhen YanZhen, Liu Chengxiang, Su Zhen; Mi Fushun, Su Xueqing, Shen Yu, Wang Jianzhang. (1992)  Investigation of Tumorigenic Effect on Ultraweak Luminescence from Nude Mouse for Animal Model    Chinese Journal of Cancer Research   Vol. 4  No. 4: 46-50

临床组  申文江等; 物理组  唐锦华, 常崴克, 张仲纶, 罗醒萱, 苏震. (1992)   快中子治疗临床实验研究    《中华放射肿瘤学杂志》   1992 (4)

张仲纶, 王英彦, 郑雁珍, 苏震, 马玉琴, 赵克俭, 刘成祥, 马斌.  (1991)    用于环境生物监测的微弱发光测量仪 《环境保护》 1991 (10) 28-29

 

专利:

1.   张仲纶,付世密,郑雁珍,苏震,马玉琴,刘成祥,江丕栋   “微弱发光测量仪”,专利号ZL96241369.0

2.   Guangzhou Zou, Xun Wang, and Zhen Su.  System and Method for Clustering Data (2003) in USA, PCT/US2003/001806

3.   孙传清,刘凤霞,谭禄宾,苏震,朱作峰,付永彩     “一种辅助筛选耐冷水稻的方法与其专用引物”,专利号ZL200610089799.1

4.   孙传清,刘凤霞,谭禄宾,苏震,朱作峰,付永彩     “辅助筛选耐冷水稻的方法和它的专用引物”  专利号200610088805.1

5.   孙传清,刘凤霞,谭禄宾,苏震,朱作峰,付永彩    “辅助筛选耐冷水稻的方法与其专用引物”       专利号200610088803.2

6.   孙传清,刘凤霞,谭禄宾,苏震,朱作峰,付永彩    “一种辅助筛选耐冷水稻的方法及其专用引物”   专利号200610088801.3

7.   孙传清,刘凤霞,谭禄宾,苏震,朱作峰,付永彩     “辅助筛选耐冷水稻的方法及其专用引物”     专利号200610089798.7

8. 孙传清,刘凤霞,苏震,谭禄宾,刘家勇,付永彩,朱作峰 “一种与植物耐冷性相关的蛋白及其编码基因与应用” 专利号200810181172.8

9.  苏震,刘凤霞,徐文英,谭禄宾,邸超,张振海,孙传清,薛勇彪    “一种辅助筛选籼稻和粳稻的方法以及专用引物”    专利号200810056529.X

10.  苏震,刘凤霞,徐文英,谭禄宾,邸超,张振海,孙传清,薛勇彪    “一种辅助筛选籼稻和粳稻的方法”  专利号200810056530.2 

11.  苏震,徐文英,于静娟,赵琳娜,刘凤霞,周少霞    “一种植物耐低温蛋白及其编码基因与应用”    专利号200810115174.7

12.  苏震,徐文英,于静娟,赵琳娜,刘凤霞,周少霞    “植物耐低温蛋白及其编码基因与应用”    专利号200810115175.1

13.  苏震,徐文英,邸超,周少霞,张盖华      “水稻细胞色素P450基因专用引物辅助鉴别植物培养基质中除草剂的残留”      专利号200810118016.7

14.  苏震,徐文英,邸超,周少霞,张盖华      “水稻细胞色素P450基因专用引物辅助鉴别植物培养基质中除草剂的残留”      专利号200810118017.1

15.  苏震,徐文英,邸超,周少霞,张盖华      “水稻细胞色素P450基因专用引物辅助鉴别植物培养基质中除草剂的残留”      专利号200810118021.8

16.  苏震,徐文英,邸超,周少霞,张盖华      “水稻细胞色素P450基因专用引物辅助鉴别植物培养基质中除草剂的残留”      专利号200810118019.0

17.  苏震,徐文英,邸超,周少霞,张盖华      “水稻细胞色素P450基因专用引物辅助鉴别植物培养基质中除草剂的残留”      专利号200810118020.3

18. 孙传清,刘凤霞,谭禄宾,付永彩,朱作峰,谢道昕,苏震 “水稻冷诱导启动子p-LTT7 及其应用” 专利号 201010122399.2

19. 孙传清,刘加勇,刘凤霞,谭禄宾,付永彩,朱作峰,苏震 “植物耐冷相关蛋白LTT9及其编码基因和应用” 专利号 201210072826.X

20. 孙传清,张侠,刘凤霞,王娜,苏震,谭禄宾,朱作峰,付永彩,谢道昕 “耐旱相关蛋白DT1及其编码基因和应用” 专利号 201110296327.4

21. 苏震,徐文英,魏强,王玲,刘凤霞,于静娟,赵琳娜,张群莲,王春超 “水稻OsSPX1蛋白及其编码基因在调控植物种子结实率中的应用” 专利号 201210101772.5

22. 苏震,徐文英,魏强,王玲,刘凤霞,于静娟,赵琳娜,张力圩 “OsSPX1蛋白及其编码基因在调节植物花粉育性中的应用” 专利号201210253451.7

23. 苏震,徐文英,魏强,王玲,刘凤霞,于静娟,赵琳娜,谭远军 “水稻OsSPX1蛋白及其编码基因在调控植物抗氧化性中的应用” 专利号 201210166813.9  

24. 李付广,王倩华,张雪妍,刘传亮,张朝军,武芝霞,王晔,孔德培,秦文强,苏震,徐文英,姚冬霞,张群莲,郑雪 “与植物抗逆性相关蛋白Gh01399 及其编码基因与应用” 专利号201210261882.8

25. 苏震,徐文英,杨教童, 张群莲,邸超,刘凤霞, 焦远年, 张康 “一种植物开花时间性状相关蛋白AtJAZ5及其编码基因和应用” 专利号 201910079723.8

26.   苏震,徐文英,闫恒宇,刘凤霞,王春超  “一种植物衰老相关蛋白AtSPX1及其编码基因和应用” 专利号  201811569253.5

27.   苏震,徐文英,赵楠楠,魏强,张群莲  “水稻组蛋白去乙酰化酶基因HDA710在延迟叶片衰老中的应用” 专利号  201911298782.0

28.   葛晓阳,李付广,苏震,徐文英,达玲玲,詹晶晶,姚冬霞,张力圩  “miR164a在应答亚洲棉耐盐中的应用” 专利号  202010952096.7

29.   葛晓阳,李付广,苏震,徐文英,达玲玲,詹晶晶,姚冬霞,张力圩  “一种亚洲棉miR172c在调控目的植物应答盐胁迫中的应用”  专利号  202010149664.X

30.   苏震,徐文英,达玲玲, 宋倩, 刘凤霞,张群莲  “拟南芥PHO1;H10蛋白及其编码基因在调控植物叶片花青素合成中的应用” 专利号  201911323001.9

 

软件著作权:

1.   杨仁东,苏震,徐文英     ARSER表达谱波形分析软件    计算机软件著作权    登记号 :2010SRBJ3476;证书号:BJ28859

2.   杨仁东,张臣,苏震,徐文英     基于Lomb-Scargle周期图回归算法软件   计算机软件著作权    登记号 :2010SRBJ6734;证书号:BJ28859

3. 张盖华,苏震     基于BMCD细胞色素P450同源结构建模流程软件   计算机软件著作权    登记号 2013SRBJ0529;证书号:BJ39206

4. 苏震,易欣     PlantGSEA植物GeneSet富集分析软件   计算机软件著作权    登记号 2013SRBJ0679;证书号:BJ39356

5.  苏震,徐文英,张振海,尤琪,于娟      顺式作用元件motif显著性分析软件      计算机软件著作权    登记号 :2015SRBJ0087;证书号:BJ40645

6. 苏震,尤琪,徐文英      同源基因共表达网络比较分析软件V1.0      计算机软件著作权      登记号 :2017SRBJ0778;证书号:BJ43322

7. 苏震,尤琪,徐文英,刘悦,田甜,马雪莲      共表达网络表达谱动态分析软件V1.0      计算机软件著作权      登记号 :2017SRBJ0683;证书号:BJ43227

8. 苏震,田甜,徐文英,刘悦,闫恒宇,尤琪      富集分析P值分布计算软件      计算机软件著作权      登记号 :2017SRBJ0838;证书号:BJ43382

9. 苏震,徐文英,易欣,尤琪,闫恒宇,佘加杰,赵楠楠      基于多维组学数据的植物新转录本预测软件V1.0      计算机软件著作权      登记号 :2017SRBJ0881;证书号:BJ43425

10. 苏震,张康,徐文英      染色质状态聚类及可视化查询分析软件V1.0    计算机软件著作权    登记号 :2017SRBJ1093;证书号:BJ43637  

11. 苏震,刘悦,徐文英       染色质状态SOM聚类比较分析及可视化软件V1.0    计算机软件著作权   登记号 :2018SRBJ0863;证书号:BJ44693

12. 苏震,刘悦,徐文英       植物基因组调控元件预测软件V1.0    计算机软件著作权   登记号 :2018SRBJ1116;证书号:BJ44946  

13. 苏震,田甜,徐文英       共表达网络自定义分析工具V1.0    计算机软件著作权    登记号 :2018SRBJ1117;证书号:BJ44947

14. 苏震,田甜,徐文英       基因组共线性图谱可视化分析工具V1.0    计算机软件著作权   登记号 :2018SRBJ1118;证书号:BJ44948

15. 苏震,佘加杰,徐文英     SNP数据查询和可视化软件   计算机软件著作权    登记号 :2020SRBJ0177;证书号:BJ46487

16.   苏震,马雪莲,徐文英       自定义基因集富集分析软件       计算机软件著作权      登记号 :2021SRBJ0509;证书号:BJ47637

17.   苏震,马雪莲,徐文英       基因集富集分析优化软件       计算机软件著作权      登记号 :2021SRBJ0558;证书号:BJ47686

18.   苏震,马雪莲,徐文英       基因集富集结果平行比较分析软件       计算机软件著作权      登记号 :2021SRBJ0563;证书号:BJ47691

 

学术奖励:

苏震,杜舟,杨仁东,周鑫,易欣,张振海 ,徐文英,凌毅,尤琪 “组学大数据整合与解析的新技术和算法研究” 2018年获 教育部高等学校科学研究优秀成果奖自然科学二等奖      证书号 :2018-068

 

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